Prof. Dr. Holger Dobbek

Research interests

Enzymology of reductive CO/CO2 metabolism in bacteria, oxidation state dependent host-guest recognition in biology, molybdoenzymes, iron-sulfur cluster, flavoenzymes, X-ray crystallography

Research Fields in UniCat

Research Field E1
Research Field E2
Research Field E3
Research Field E4

2007-2011: B2

Selection of research projects

  • Stabilization and characterization of various adducts bound to enzymes containing O2-sensitive iron-sulfur cluster
  • Analysing the function of flavoenzymes by combining single-turnover kinetics and X-ray crystallography
  • Structural analysis of an O2-sensitive Mo-Se containing enzyme

UniCat publications

672 n-Butyl isocyanide oxidation at the [NiFe4S4OHx] cluster of CO dehydrogenase J. H. Jeoung, H. Dobbek Journal of Biological Inorganic Chemistry 2011, 0, 0 - 0,

641 Crystal structure of the ATP-dependent maturation factor of Ni,Fe-containing carbon monoxide dehydrogenases J. H. Jeoung, T. Giese, M. Grünwald, H. Dobbek Journal of Molecular Biology 2010, 396, 1165 - 1179, 10.1016/j.jmb.2009.12.062

640 Structural basis of cyanide inhibition of Ni, Fe-containing carbon monoxide dehydrogenase J. H. Jeoung, H. Dobbek Journal of the American Chemical Society 2009, 131, 9922 - 9923, 10.1021/ja9046476

639 Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-CoA Pathway S. Goetzl, J. H. Jeoung, S. Hennig, H. Dobbek Journal of Molecular Biology 2011, 411, 96 - 109, 10.1016/j.jmb.2011.05.025

611 Structural aspects of mononuclear Mo/W-enzymes H. Dobbek Coordination Chemistry Reviews 2011, 255, 1104 - 1116,

Prof. Dr. Holger Dobbek

Photo of Holger  Dobbek

Holger Dobbek
Humboldt Universität zu Berlin
Institut für Biologie Strukturbiologie/Biochemie
Invalidenstraße 43
10115 Berlin

030 2093-6369
holger.dobbek(at)biologie.hu-berlin.de

 

 

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