Prof. Dr. Bärbel Friedrich
Research interests
Hydrogenase characterisation, physiology and biochemistry
Research Fields in UniCat
Research Field E3
Research Field E4
Selection of research projects
UniCat publications
| 780 Probing the origin of the metabolic precursor of the CO ligand in the catalytic center of [NiFe]-hydrogenase I. Bürstel, P. Hummel, E. Siebert, N. Wisitruangsakul, I. Zebger, B. Friedrich, O. Lenz Journal of Biological Chemistry 2011, 286, 44937 - 44944, 10.1074/jbc.M111.309351 |
| 775 A Trimeric Supercomplex of the Oxygen-Tolerant Membrane-Bound [NiFe]-Hydrogenase from Ralstonia eutropha H16 S. Frielingsdorf, T. Schubert, A. Pohlmann, O. Lenz, B. Friedrich Biochemistry 2011, 50, 10836 - 10843, 10.1021/bi201594m |
| 772 The functional role of cytochrome b in the electron transfer pathway of the membrane bound hydrogenase from Re immobilized on electrodes M. Sezer, S. Frielingsdorf, D. Millo, I. Zebger, T. Utesch, M. A. Mroginski, N. Heidary, B. Friedrich, P. Hildebrandt, I. Weidinger Journal of Physical Chemistry B 2011, 115, 10368 - 10374, |
| 762 Oxygen-Tolerant [NiFe]-Hydrogenases: The Individual and Collective Importance of Supernumerary Cysteines at the Proximal Fe-S Cluster M. J. Lukey, M. M. Roessler, A. Parkin, R. M. Evans, R. A. Davies, O. Lenz, B. Friedrich, F. Sargent, F. A. Armstrong Journal of the American Chemical Society 2011, 133, 16881 - 16892, dx.doi.org/10.1021/ja205393w |
| 760 [NiFe] and [FeS] Cofactors in the Membrane-Bound Hydrogenase of Ralstonia eutropha Investigated by X-ray Absorption Spectroscopy: Insights into O2-Tolerant H2 Cleavage F. Johannes, S. Löscher, O. Sanganas, E. Siebert, I. Zebger, M. Stein, M. Ludwig, A. L. De Lacey, H. Dau, B. Friedrich, O. Lenz, M. Haumann Biochemistry 2011, 50, 5858 - 5869, dx.doi.org/10.1021/bi200367u |
| 728 The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre J. Fritsch, P. Scheerer, S. Frielingsdorf, S. Kroschinsky, B. Friedrich, O. Lenz, C. Spahn Nature 2011, 479, 249 - 252, 10.1038/nature10505 |
| 665 Oxygen-tolerant hydrogenases in hydrogen-based technologies B. Friedrich, J. Fritsch, O. Lenz Current Opinion in Biotechnology 2011, 22, 358 - 364, 10.1016/j.copbio.2011.01.006 |
| 578 The maturation factors HoxR and HoxT contribute to oxygen tolerance of membrane-bound [NiFe] hydrogenase in Ralstonia eutropha H16 J. Fritsch, O. Lenz, B. Friedrich Journal of Bacteriology 2011, 193, 2487 - 2497, 10.1128/JB.01427-10 |
| 577 A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase T. Goris, A. F. Wait, M. Saggu, J. Fritsch, N. Heidary, M. Stein, I. Zebger, F. Lendzian, F. A. Armstrong, B. Friedrich, O. Lenz Nature Chemical Biology 2011, 7, 310 - 318, 10.1038/NCHEMBIO.555 |
| 456 Oxygen-tolerant hydrogenases in hydrogen-based technologies B. Friedrich, J. Fritsch, O. Lenz Current Opinion in Biotechnology 2011, 22, 358 - 364, 10.1016/j.copbio.2011.01.006 |
| 434 Gas pressure effects on the rates of catalytic H2 oxidation by hydrogenases J. Cracknell, B. Friedrich, F. Armstrong Chemical Communications 2010, 46, 8463 - 8465, 10.1039/C0CC03292A |
| 421 Protein complex formation affects the Ni-Fe and Fe-S centers of H2-sensing regulatory hydrogenase from Ralstonia eutropha H16 S. Löscher, A. Gebler, M. Stein, O. Sanganas, T. Buhrke, I. Zebger, H. Dau, B. Friedrich, M. Haumann ChemPhysChem 2010, 11, 1297 - 1306, 10.1002/cphc.200901007 |
| 381 Protein complex formation affects the Ni-Fe and Fe-S centers of H2-sensing regulatory hydrogenase from Ralstonia eutropha H16 M. Stein, A. Gebler, S. Löscher, O. Sanganas, T. Buhrke, I. Zebger, H. Dau, B. Friedrich, O. Lenz, M. Haumann ChemPhysChem 2010, 11, 1297 - 1306, 10.1002/cphc.200901007 |
| 355 H2 conversion in the presence of O2 as performed by the membrane-bound [NiFe]-hydrogenase of Ralstonia eutropha O. Lenz, M. Ludwig, T. Schubert, I. Buerstel, S. Ganskow, T. Goris, A. Schwarze, B. Friedrich ChemPhysChem 2010, 11, 1107 - 1119, 10.1002/cphc.200901002 |
| 349 Impact of amino acid substitutions near the catalytic site on the spectral properties of an O2-tolerant membrane-bound [NiFe]-hydrogenase M. Saggu, M. Ludwig, B. Friedrich, P. Hildebrandt, R. Bittl, F. Lendzian, O. Lenz, I. Zebger ChemPhysChem 2010, 11, 1215 - 1224, 10.1002/cphc.200900988 |
| 348 Photosynthetic hydrogen production by a hybrid complex of photosystem I and [NiFe]-hydrogenase H. Krassen, A. Schwarze, B. Friedrich, K. Ataka, O. Lenz, J. Heberle ACS Nano 2009, 3, 4055 - 4061, 10.1021/nn900748j |
| 347 A kinetic and thermodynamic understanding of O2 tolerance in [NiFe]-hydrogenases J. A. Cracknell, A. F. Wait, O. Lenz, B. Friedrich, F. A. Armstrong Proceedings of the National Academy of Sciences of the United States of America 2009, 106, 20681 - 20686, 10.1073/pnas.0905959106 |
| 345 Comparison of the membrane-bound [NiFe] hydrogenases from R. eutropha H16 and D. vulgaris Miyazaki F in the oxidized ready state by pulsed EPR M. Saggu, C. Teutloff, M. Ludwig, M. Brecht, M. E. Pandelia, O. Lenz, B. Friedrich, W. Lubitz, P. Hildebrandt, F. Lendzian, R. Bittl Physical Chemistry Chemical Physics 2010, 12, 2139 - 2148, 10.1039/b922236g |
| 136 Enzymatic oxidation of H2 in atmospheric O2: The electrochemistry of energy generation from trace H2 by aerobic by aerobic microorganisms J. A. Cracknell, K. A. Vincent, M. Ludwig, O. Lenz, B. Friedrich, F. A. Armstrong Journal of the American Chemical Society 2008, 130, 424 - 425, 10.1021/ja078299 |
| 135 Hydrogen production under aerobic conditions by membrane-bound hydrogenases from Ralstonia species G. Goldet, A. F. Wait, J. A. Cracknell, K. A. Vincent, M. Ludwig, O. Lenz, B. Friedrich, F. A. Armstrong Journal of the American Chemical Society 2008, 130, 11106 - 11113, 10.1021/ja8027668 |
| 133 Concerted action of two novel auxiliary proteins in assembly of the active site in a membrane-bound [NiFe]-hydrogenase M. Ludwig, T. Schubert, I. Zebger, N. Wisitruangsakul, M. Saggu, A. Strack, O. Lenz, P. Hildebrandt, B. Friedrich The Journal Of Biological Chemistry 2009, 284, 2159 - 2168, 10.1074/jbc.M808488200 |
| 131 Oxygen-tolerant H2 oxidation by membrane-bound [NiFe]-hydrogenase of Ralstonia species: Coping with low-level H2 in air M. Ludwig, J. A. Cracknell, K. A. Vincent, F. A. Armstrong, O. Lenz The Journal Of Biological Chemistry 2009, 284, 465 - 477, 10.1074/jbc.M803676200 |
| 130 Knallgas unter Kontrolle: O2-tolerante Hydrogenasen und ihre Anwendung M. Ludwig, A. Schwarze, O. Lenz BIOspektrum 2008, 5, 477 - 479, |
| 129 Biokatalysatoren für die Erzeugung von Wasserstoff und Strom O. Lenz, B. Friedrich Aktuelle Wochenschau (Online) 2008, 0, 0 - 0, |
| 52 Spectroscopic insight into the oxygen-tolerant membrane-associated [NiFe]-hydrogenase of Ralstonia eutropha H16 M. Saggu, I. Zebger, M. Ludwig, O. Lenz, B. Friedrich, P. Hildebrandt, F. Lendzian Journal of Biological Chemistry 2009, 284, 16264 - 16276, 10.1074/jbc.M805690200 |
| 49 Untersuchung des Katalyseprozesses der membrangebundenen Hydrogenase aus Rastolnia EutrophaH16 mittels oberflächenverstärkter Infrarotabsorptionsspektroskopie N. Wisitruangsakul, O. Lenz, M. Ludwig, B. Friedrich, P. Hildebrandt, F. Lendzian, I. Zebger Angewandte Chemie 2009, 121, 621 - 623, 10.1002/ange.200802633 |
| 48 Monitoring catalysis of the membrane-bound hydrogenase of Rastolnia Eutropha by surface enhanced infrared absorption spectroscopy N. Wisitruangsakul, O. Lenz, M. Ludwig, B. Friedrich, P. Hildebrandt, F. Lendzian, I. Zebger Angewandte Chemie International Edition 2009, 48, 611 - 613, 10.1002/anie.200802633 |
