Prof. Dr. Silke Leimkühler
Research interests
Molybdoenzymes, biochemistry
Research Fields in UniCat
Research Field E2
Research Field E3
2007-2011: B3
Selection of research projects
UniCat publications
| 779 A Crystallographic and Mo K-Edge XAS study of molybdenum oxo bis-mono-, and non-dethiolene komplexes - first-sphere coordination geometry and noninnocence of ligands P. Samuel, S. Horn, A. Döring, K. Havelius, S. Reschke, S. Leimkühler, M. Haumann, C. Schulzke European Journal of Inorganic Chemistry 2011, 2011, 4387 - 4399, 10.1002/ejic.201100331 |
| 778 Characterization and Crystallization of mouse aldehyde oxidase 3: from mouse liver to Escherichia coli heterologous protein expression M. Mahro, C. Coelho, J. Trincao, D. Rodrigues, M. Terao, E. Garattini, M. Saggu, F. Lendzian, P. Hildebrandt, M. Romao, S. Leimkühler Drug Metabolism and Disposition 2011, 39, 1939 - 1945, |
| 492 Redox properties and catalytic activity of surface-bound human sulfite oxidase studied by a combined surface enhanced resonance Raman spectroscopic and electrochemical approach M. Sezer, R. Spricigo, T. Utesch, D. Millo, S. Leimkühler, M. A. Mroginski, U. Wollenberger, P. Hildebrandt, I. Weidinger Physical Chemistry Chemical Physics 2010, 12, 7894 - 7903, |
| 446 Xanthine Dehydrogenase P. Kalimuthu, S. Leimkühler, P. V. Bernhardt Journal of Physical Chemistry B 2011, 115, 2655 - 2662, 10.1021/jp111809f |
| 430 The history of the discovery of the molybdenum cofactor and novel aspects of its biosynthesis in bacteria. S. Leimkühler, M. Wuebbens, K. V. Rajagopalan Coordination Chemistry Reviews 2011, 255, 1129 - 1144, 10.1016/j.ccr.2010.12.003 |
| 429 The Biosynthesis of Folate and Pterins and Their Enzymology M. Fischer, B. Thöny, S. Leimkühler Comprehensive Natural Products II Chemistry and Biology (L. Mander, H-W. Liu - Elsevier) Mander, L., Lui, H.-W., Eds. Elsevier: Oxford 2010, 7, 599 - 648, |
| 422 Structure of the Molybdenum Site in YedY, a Sulfite Oxidase Homologue from Escherichia coli K. Havelius, S. Reschke, S. Horn, A. Döring, D. Nicks, R. Hille, C. Schulzke, S. Leimkühler, M. Haumann Inorganic Chemistry 2011, 50, 741 - 748, 10.1021/ic101291j |
| 238 Sulfite biosensor based on osmium redox polymer wired sulfite oxidase R. Spricigo, C. Richter, S. Leimkühler, L. Gorton, F. Scheller, U. Wollenberger Colloids and Surfaces A: Physicochemical and Engineering Aspects 2010, 354, 314 - 319, 10.1016/j.colsurfa.2009.09.001 |
| 17 Electrocatalytic sulfite biosensor with human sulfite oxidase coimmobilized with cytochrome c in a polyelectrolyte containing multilayer R. Spricigo, R. Dronov, F. Lisdat, S. Leimkühler, F. Scheller, U. Wollenberger Analytical and Bioanalytical Chemistry 2009, 393, 225 - 233, 10.1007/s00216-008-2432-y |
| 13 The mechanism of assembly and cofactor insertion into Rhodobacter capsulatus xanthine dehydrogenase S. Schumann, M. Saggu, N. Moeller, S. D. Anker, F. Lendzian, P. Hildebrandt, S. Leimkühler The Journal Of Biological Chemistry 2008, 283, 16602 - 16611, 10.1074/jbc.M709894200 |
| 12 A periplasmic aldehyde oxidoreductase represents the first molybdopterin cytosine dinucleotide cofactor containing molybdo-flavoenzyme from Escherichia coli M. Neumann, G. Mittelstaedt, C. Iobbi-Nivol, M. Saggu, F. Lendzian, P. Hildebrandt, S. Leimkühler FEBS Journal 2009, 276, 2762 - 2774, 10.1111/j.1742-4658.2009.07000.x |
| 11 Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1 S. Schumann, M. Terao, E. Garattini, M. Saggu, F. Lendzian, P. Hildebrandt, S. Leimkühler PLoS ONE 2009, 4, 5348 - 5348, 10.1371/journal.pone.0005348 |
Patents
Biosensor for measuring GABA, U. Wollenberger, A. Badalyan, C. Stiba, S. Leimkühler, filed on 2011, EP
