PD Dr. Michael Haumann

Heisenberg fellow of German Research Foundation (DFG)

Research interests

Molecular biophysics, metalloenzymes, x-ray spectroscopy

Research Fields in UniCat

2007-2010: A5, B1, B2, B3

UniCat publications

2396 From an Fe2P3complex to FeP nanoparticles as efficient electrocatalysts for water-splitting S. Yao, V. Forstner, P. W. Menezes, C. Panda, S. Mebs, E. M. Zolnhofer, M. E. Miehlich, T. Szilvási, N. Ashok Kumar, M. Haumann, K. Meyer, H. Grützmacher, M. Driess Chemical Science 2018, 9, 8590–8597, 10.1039/C8SC03407A

2339 Kα X-ray Emission Spectroscopy on the Photosynthetic Oxygen-Evolving Complex Supports Manganese Oxidation and Water Binding in the S3State N. Schuth, I. Zaharieva, P. Chernev, G. Berggren, M. Anderlund, S. Styring, H. Dau, M. Haumann Inorganic Chemistry 2018, 57, 10424–10430, 10.1021/acs.inorgchem.8b01674

2323 O2-Tolerant H2Activation by an Isolated Large Subunit of a [NiFe] Hydrogenase S. Hartmann, S. Frielingsdorf, A. Ciaccafava, C. Lorent, J. Fritsch, E. Siebert, J. Priebe, M. Haumann, I. Zebger, O. Lenz Biochemistry 2018, 57, 5339–5349, 10.1021/acs.biochem.8b00760

2248 Ligand binding at the A-cluster in full-length or truncated acetyl-CoA synthase studied by X-ray absorption spectroscopy P. Schrapers, J. Ilina, C. M. Gregg, S. Mebs, J. H. Jeoung, H. Dau, H. Dobbek, M. Haumann PLOS ONE 2017, 12, 10.1371/journal.pone.0171039

2225 Effective intermediate-spin iron in O2-transporting heme proteins N. Schuth, S. Mebs, D. Huwald, P. Wrzolek, M. Schwalbe, A. Hemschemeier, M. Haumann Proceedings of the National Academy of Sciences 2017, 114, 8556–8561, 10.1073/pnas.1706527114

2183 Protonation and Sulfido versus Oxo Ligation Changes at the Molybdenum Cofactor in Xanthine Dehydrogenase (XDH) Variants Studied by X-ray Absorption Spectroscopy S. Reschke, S. Mebs, K. G. V. Sigfridsson-Clauss, R. Kositzki, S. Leimkühler, M. Haumann Inorganic Chemistry 2017, 56, 2165–2176, 10.1021/acs.inorgchem.6b02846

2060 Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT P. Schrapers, S. Mebs, S. Goetzl, S. E. Hennig, H. Dau, H. Dobbek, M. Haumann PLOS ONE 2016, 11, 10.1371/journal.pone.0158681

2009 The Molybdenum Active Site of Formate Dehydrogenase Is Capable of Catalyzing C–H Bond Cleavage and Oxygen Atom Transfer Reactions T. Hartmann, P. Schrapers, T. Utesch, M. Nimtz, Y. Rippers, H. Dau, M. A. Mroginski, M. Haumann, S. Leimkühler Biochemistry 2016, 55, 2381–2389, 10.1021/acs.biochem.6b00002

1837 Sulfido and Cysteine Ligation Changes at the Molybdenum Cofactor during Substrate Conversion by Formate Dehydrogenase (FDH) fromRhodobacter capsulatus P. Schrapers, T. Hartmann, R. Kositzki, H. Dau, S. Reschke, C. Schulzke, S. Leimkühler, M. Haumann Inorganic Chemistry 2015, 54, 3260–3271, 10.1021/ic502880y

1817 Biomimetische [2Fe-2S]-Cluster mit stark delokalisierten gemischtvalenten Eisenzentren S. Yao, F. Meier, N. Lindenmaier, R. Rudolph, B. Blom, M. Adelhardt, J. Sutter, S. Mebs, M. Haumann, K. Meyer, M. Kaupp, M. Driess Angewandte Chemie 2015, 127, 12686–12690, 10.1002/ange.201506788

1716 Biomimetic [2Fe-2S] Clusters with Extensively Delocalized Mixed-Valence Iron Centers S. Yao, F. Meier, N. Lindenmaier, R. Rudolph, B. Blom, M. Adelhardt, J. Sutter, S. Mebs, M. Haumann, K. Meyer, M. Kaupp, M. Driess Angewandte Chemie International Edition 2015, 54, 12506–12510, 10.1002/anie.201506788

1639 Structural differences of oxidized iron−sulfur and nickel−iron cofactors in O2-tolerant and O2-sensitive hydrogenases studied by X-ray absorption spectroscopy K. G. V. Sigfridsson, N. Leidel, O. Sanganas, P. Chernev, O. Lenz, K. S. Yoon, H. Nishihara, A. Parkin, F. A. Armstrong, S. Dementin, M. Rousset, A. L. De Lacey, M. Haumann Biochimica et Biophysica Acta (BBA) - Bioenergetics 2015, 1847, 162–170, 10.1016/j.bbabio.2014.06.011

1537 Hydride Binding to the Active Site of [FeFe]-Hydrogenase P. Chernev, C. Lambertz, A. Brünje, N. Leidel, K. G. V. Sigfridsson, R. Kositzki, C. H. Hsieh, S. Yao, R. Schiwon, M. Driess, C. Limberg, T. Happe, M. Haumann Inorganic Chemistry 2014, 53, 12164–12177, 10.1021/ic502047q

1354 Effect of Exchange of the Cysteine Molybdenum Ligand with Selenocysteine on the Structure and Function of the Active Site in Human Sulfite Oxidase S. Reschke, D. Niks, H. Wilson, K. G. V. Sigfridsson, M. Haumann, K. V. Rajagopalan, R. Hille, S. Leimkühler Biochemistry 2013, 52, 8295–8303, 10.1021/bi4008512

1261 Iron–molybdenum-oxo complexes as initiators for olefin autoxidation with O2 J. P. Falkenhagen, C. Limberg, S. Demeshko, S. Horn, M. Haumann, B. Braun, S. Mebs Dalton Transactions 2014, 43, 806– 10.1039/c3dt52349g

1227 Protein-Protein Complex Formation Affects the Ni-Fe and Fe-S Centers in the H2-Sensing Regulatory Hydrogenase from Ralstonia eutropha H16 S. Löscher, A. Gebler, M. Stein, O. Sanganas, T. Buhrke, I. Zebger, H. Dau, B. Friedrich, O. Lenz, M. Haumann ChemSusChem 2010, 11, 1297–1306, 10.1002/cphc.200901007

1123 Identification of a bis-molybdopterin intermediate in molybdenum cofactor biosynthesis in Escherichia coli S. Reschke, K. G. V. Sigfridsson, P. Kaufmann, N. Leidel, S. Horn, K. Gast, C. Schulzke, M. Haumann, S. Leimkuehler Journal of Biological Chemistry 2013, 288, 29736–29745, 10.1074/jbc.M113.497453

926 High-valent [MnFe] and [FeFe] cofactors in ribonucleotide reductases N. Leidel, A. Popović-Bijelić, K. Havelius, P. Chernev, N. Voevodskaya, A. Gräslund, M. Haumann Biochimica et Biophysica Acta 2012, 1817, 430–444, 10.1016/j.bbabio.2011.12.008

925 Electronic structure of an [FeFe] hydrogenase model complex in solution revealed by X-ray absorption spectroscopy using narrow-band emission detection N. Leidel, P. Chernev, K. Havelius, L. Schwartz, S. Ott, M. Haumann Journal of the American Chemical Society 2012, 134, 14142–14157, 10.1021/ja304970p

924 Site-selective X-ray spectroscopy on an asymmetric model complex of the [FeFe] hydrogenase active site N. Leidel, P. Chernev, K. Havelius, S. Ezzaher, S. Ott, M. Haumann Inorganic Chemistry 2012, 51, 4546–4559, 10.1021/ic2024154

923 Alternating electron and proton transfer steps in photosynthetic water oxidation A. Klauss, M. Haumann, H. Dau Proc Natl Acad Sci U S A 2012, 109, 16035–16040, 10.1073/pnas.1206266109

921 Recent developments in research on water oxidation by photosystem II H. Dau, I. Zaharieva, M. Haumann Current Opinion in Chemical Biology 2012, 16, 3–10, 10.1016/j.cbpa.2012.02.011

917 O2 Reactions at the Six-iron Active Site (H-cluster) in [FeFe]-Hydrogenase C. Lambertz, N. Leidel, K. Havelius, J. Noth, P. Chernev, M. Winkler, T. Happe, M. Haumann Journal of Biological Chemistry 2011, 286, 40614–40623, 10.1074/jbc.M111.283648

779 A Crystallographic and Mo K-Edge XAS study of molybdenum oxo bis-mono-, and non-dethiolene komplexes - first-sphere coordination geometry and noninnocence of ligands P. Samuel, S. Horn, A. Döring, K. Havelius, S. Reschke, S. Leimkühler, M. Haumann, C. Schulzke European Journal of Inorganic Chemistry 2011, 2011, 4387–4399, 10.1002/ejic.201100331

760 [NiFe] and [FeS] Cofactors in the Membrane-Bound Hydrogenase of Ralstonia eutropha Investigated by X-ray Absorption Spectroscopy: Insights into O2-Tolerant H2 Cleavage F. Johannes, S. Löscher, O. Sanganas, E. Siebert, I. Zebger, M. Stein, M. Ludwig, A. L. De Lacey, H. Dau, B. Friedrich, O. Lenz, M. Haumann Biochemistry 2011, 50, 5858–5869, 10.1021/bi200367u

581 Synthetic manganese-calcium oxides mimic the water-oxidizing complex of photosynthesis functionally and structurally I. Zaharieva, M. M. Najafpour, M. Wiechen, M. Haumann, P. Kurz, H. Dau Energy & Environmental Science 2011, 4, 2400–2408, 10.1039/c0ee00815j

458 The Hydrogenase Subcomplex of the NAD+-Reducing [NiFe] Hydrogenase from Ralstonia eutropha - Insights into Catalysis and Redox Interconversions L. Lauterbach, J. Liu, M. Horch, P. Hummel, A. Schwarze, M. Haumann, K. A. Vincent, O. Lenz, I. Zebger European Journal of Inorganic Chemistry 2011, 7, 1067–1079, 10.1002/ejic.201001053

424 The FeFe hydrogenase maturation protein HydF contains a H-cluster like [4Fe-4S]-2Fe site I. Czech, S. Stripp, O. Sanganas, N. Leidel, T. Happe, M. Haumann FEBS letters 2011, 585, 225–230, 10.1016/j.febslet.2010.11.052

423 Carboxylate shifts steer inter-quinone electron transfer in photosynthesis P. Chernev, I. Zaharieva, H. Dau, M. Haumann The Journal Of Biological Chemistry 2011, 286, 5368–5374, 10.1074/jbc.M110.202879

422 Structure of the Molybdenum Site in YedY, a Sulfite Oxidase Homologue from Escherichia coli K. Havelius, S. Reschke, S. Horn, A. Döring, D. Nicks, R. Hille, C. Schulzke, S. Leimkühler, M. Haumann Inorganic Chemistry 2011, 50, 741–748, 10.1021/ic101291j

385 Facilitated hydride binding in an Fe-Fe hydrogenase active-site biomimic revealed by X-ray absorption spectroscopy and DFT calculations S. Löscher, L. Schwartz, M. Stein, S. Ott, M. Haumann Inorganic Chemistry 2007, 46, 11094–11105, 10.1021/ic701255p

384 The structure of the active site H-cluster of [FeFe] hydrogenase from the green alga Chlamydomonas reinhardtii studied by X-ray absorption spectroscopy S. Stripp, O. Sanganas, T. Happe, M. Haumann Biochemistry 2009, 48, 5042–5049, 10.1021/bi900010b

383 Introduction of methionines in the gas channel makes [NiFe] hydrogenase aero-tolerant S. Champ, L. Martin, S. Dementin, F. Leroux, L. Cournac, A. De Lacey, A. Volbeda, C. Leger, B. Burlat, N. Martinez, O. Sanganas, M. Haumann, V. Fernandez, B. Guigliarelli, J. Fontecilla-Camps, M. Rousset Journal of the American Chemical Society 2009, 131, 10156–10164, 10.1021/ja9018258

382 How oxygen attacks [FeFe] hydrogenases from photosynthetic organisms S. Stripp, G. Goldet, C. Brandmayr, O. Sanganas, K. A. Vincent, M. Haumann, F. A. Armstrong, T. Happe Proceedings of the National Academy of Sciences of the United States of America 2009, 106, 17331–17336, 10.1073/pnas.0905343106

367 Towards a comprehensive X-ray approach for studying the photosynthetic manganese complex-XANES, K Alpha/K Beta/K Beta-satellite emission lines, RIXS, and comparative computational approaches for selected model complexes I. Zaharieva, P. Chernev, M. Risch, L. Gerencser, G. Bergren, D. Shevchenko, M. Anderlund, T. C. Weng, M. Haumann, H. Dau Journal of Physics: Conference Series 2009, 190, 1–6, 10.1088/1742-6596/190/1/012142

292 Resonant inelastic X-ray scattering on synthetic nickel compounds and Ni-Fe hydrogenase protein O. Sanganas, S. Löscher, S. Pfirrmann, N. Marinos, P. Glatzel, T. C. Weng, C. Limberg, M. Driess, H. Dau, M. Haumann Journal of Physics: Conference Series 2009, 190, 12199–12199, 10.1088/1742-6596/190/1/012199

145 The manganese complex of photosystem II in its reaction cycle - basic framework and possible realization at the atomic level H. Dau, M. Haumann Coordination Chemistry Reviews 2008, 252, 273–295, 10.1016/j.ccr.2007.09.001

144 Photosynthetic water oxidation at elevated dioxygen partial pressure monitored by time-resolved X-ray absorption measurements M. Haumann, A. Grundmeier, I. Zaharieva, H. Dau Proceedings of the National Academy of Sciences of the United States of America 2008, 105, 17384–17389, 10.1073/pnas.0802596105

PD Dr. Michael Haumann

Michael Haumann
Freie Universität zu Berlin
Institut für Experimentalphysik
Arnimallee 14
Berlin , 14195
+49 30 838-56101/ -56299